Matthews RA. Medical progress depends on animal models - doesn't it? J R Soc Med 2008: 101: 95–98. DOI 10.1258/jrsm.2007.070164. Download (149 kb).

OVERVIEW
Critical assessment of the oft-repeated claim that ‘Virtually every medical achievement of the last century has depended directly or indirectly on research with animals.’ Includes a quantitative analysis of the predictivity for human outcomes of animal models.